HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 6-chloro-3-(2-methoxyethoxy)-1-trityl-1H-pyrazolo[4,3-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | 6-chloro-1-trityl-1H-pyrazolo[4,3-c]pyridin-3(2H)-one | HCID 118272301 | — |
| Product | 6-chloro-3-(2-methoxyethoxy)-1-trityl-1H-pyrazolo[4,3-c]pyridine | HCID 118272494 | 84% |
Reaction Steps
In a manner similar to that described in Example 1 (Step 1), 6-chloro-1-trityl-1H-pyrazolo[4,3-c]pyridin-3(2H)-one (3B) was treated with 1-bromo-2-methoxyethane and potassium carbonate (DMF, room temperature, overnight) to provide 6-chloro-3-(2-methoxyethoxy)-1-trityl-1H-pyrazolo[4,3-c]pyridine (84% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09226922B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-0324a64bad0f436c8969836001d62085 |
| Source note | uspto-grants-2016_01 |