HCID 131734430, compound → HCID 118373963, compound

Participants

Reaction Steps

(R)-Ethyl 3-(benzyloxy)-6-(3-(1-phenylethyl)ureido)-1H-pyrazolo[4,3-c]pyridine-1-carboxylate (177.2 mg, 0.386 mmol) and Pd/C (4.10 mg, 0.039 mmol) were stirred in EtOAc (3.86 mL), under a balloon of hydrogen gas for 72 h. The reaction mixture was filtered through Celite, eluting with EtOAc. The filtrate was concentrated in vacuo to afford (R)-ethyl 3-oxo-6-(3-(1-phenylethyl)ureido)-2,3-dihydro-1H-pyrazolo[4,3-c]pyridine-1-carboxylate, which was carried onto the next step without further purification. MS ESI calc'd. For C18H19N5O4 [M+1]+370. found 370.

Provenance & Evidence