HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-methyl-3-nitropyridine → Ethyl 5-((5-methyl-3-nitropyridin-2-yl)amino)picolinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-methyl-3-nitropyridine | HCID 818300 | — |
| Reactant | Ethyl 5-aminopyridine-2-carboxylate | HCID 13816714 | — |
| Product | Ethyl 5-((5-methyl-3-nitropyridin-2-yl)amino)picolinate | HCID 117652979 | 53.4% |
Reaction Steps
Prepared according to General Procedure E starting from ethyl 5-aminopicolinate (14.0 g, 84.2 mmol) and 2-chloro-5-methyl-3-nitropyridine (17.4 g, 101 mmol) to give the title compound as a yellow solid (13.6 g, 53%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227956B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-7e02379a946e45df80e56da4b1c97645 |
| Source note | uspto-grants-2016_01 |