HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)-4-methylpiperazine → 4-Chloro-3-methyl-1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-pyrazolo[3,4-c]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)-4-methylpiperazine | HCID 231184 | — |
| Reactant | CID 86717276 | HCID 86717276 | — |
| Product | 4-Chloro-3-methyl-1-[2-(4-methylpiperazin-1-yl)ethyl]-5-phenyl-pyrazolo[3,4-c]pyridazine | HCID 86717277 | — |
Reaction Steps
Compound Iv was synthesized from 4-chloro-3-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine and 2-(4-methylpiperazin-1-yl)ethanol following the general procedure for the Mitsunobu reaction described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227976B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-9c50aa049a694e0f8eaca5edc4744376 |
| Source note | uspto-grants-2016_01 |