Acetic acid, 2-hydrazinyl-, ethyl ester, hydrochloride (1:1) → HCID 86717291, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-oxo-3-pyridin-3-ylpropane nitrile (1.31 g, 9 mmol), ethyl hydrazinoacetate hydrochloride (1.39 g, 9 mmol) in methanol (9 mL) was heated under microwave irradiation at 120° C. for 1 h. The reaction mixture was concentrated in vacuo and the residue was purified by column chromatography (silica gel, ethyl acetate) yielding the title compound as a solid (510 mg).

Provenance & Evidence