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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588599Generated: October 26, 2026

1-(2-Hydroxyethyl)-2-pyrrolidinone → 1-[2-(4-Chloro-3,5-diphenyl-pyrazolo[3,4-c]pyridazin-1-yl)ethyl]pyrrolidin-2-one

https://huagongshe.com/reaction/588599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)-2-pyrrolidinoneHCID 76980—
ReactantCID 86697018HCID 86697018—
Product1-[2-(4-Chloro-3,5-diphenyl-pyrazolo[3,4-c]pyridazin-1-yl)ethyl]pyrrolidin-2-oneHCID 74221021—

Reaction Steps

Compound IIb was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and 1-(2-hydroxyethyl)pyrrolidin-2-one following the general procedure for the Mitsunobu reaction as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227976B2
Source datasetuspto-grants-2016_01
ORD IDord-6a1335bcc47244878ab177f5f509e1d5
Source noteuspto-grants-2016_01