反应详情

温度

230 °C

A mixture of 1 g methyl 1-acetylamino-2-chloro6,7,8,9-tetrahydrodibenzofuran-4-carboxylate and 0.5 g of 5% palladium-charcoal is heated under nitrogen at 230° C. for 5 hours. The cooled residue is extracted with toluene and the solvent evaporated to dryness. The residue is crystallized from ethyl acetate/hexane to give methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate.

1. extractionThe cooled residue is extracted with toluene
2. customthe solvent evaporated to dryness
3. customThe residue is crystallized from ethyl acetate/hexane