Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588600Generated: October 26, 2026

3,3,3-Trifluoro-1-propanol → 4-Chloro-3,5-diphenyl-1-(3,3,3-trifluoropropyl)pyrazolo[3,4-c]pyridazine

https://huagongshe.com/reaction/588600

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3,3-Trifluoro-1-propanolHCID 137512—
ReactantCID 86697018HCID 86697018—
Product4-Chloro-3,5-diphenyl-1-(3,3,3-trifluoropropyl)pyrazolo[3,4-c]pyridazineHCID 74221019—

Reaction Steps

Compound IId was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and 3,3,3-trifluoropropan-1-ol following the general procedure for the Mitsunobu reaction as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227976B2
Source datasetuspto-grants-2016_01
ORD IDord-bc904479c89a49159caee50ff61e8715
Source noteuspto-grants-2016_01