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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588601Generated: October 26, 2026

Tetrahydro-4H-pyran-4-ol → 4-Chloro-3,5-diphenyl-1-tetrahydropyran-4-yl-pyrazolo[3,4-c]pyridazine

https://huagongshe.com/reaction/588601

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-olHCID 74956—
ReactantCID 86697018HCID 86697018—
Product4-Chloro-3,5-diphenyl-1-tetrahydropyran-4-yl-pyrazolo[3,4-c]pyridazineHCID 74221018—

Reaction Steps

Compound IIe was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and tetrahydro-2H-pyran-4-ol following the general procedure for the Mitsunobu reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227976B2
Source datasetuspto-grants-2016_01
ORD IDord-264605c3a5604c33b6afc1b4708f936c
Source noteuspto-grants-2016_01