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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 588656Generated: October 27, 2026

Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol → 1-(2-oxatricyclo[3.3.1.13,7]dec-1-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

https://huagongshe.com/reaction/588656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTricyclo(3.3.1.1'3,7)dec-1-ylmethanolHCID 64556—
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 2774010—
Reactant3,5-Dimethylpyrazole-4-boronic acid, pinacol esterHCID 16217713—
Product1-(2-oxatricyclo[3.3.1.13,7]dec-1-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 86681259—

Reaction Steps

The title compound was prepared by substituting EXAMPLE 13A for 1-adamantanemethanol and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 2A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09227963B2
Source datasetuspto-grants-2016_01
ORD IDord-05fcfa160580448a896a23f7375e8b3e
Source noteuspto-grants-2016_01