HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → [2-(2-Methoxyethyl)tricyclo[3.3.1.13,7]dec-2-yl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | Methyl 2-(2-methoxyethyl)tricyclo[3.3.1.13,7]decane-2-carboxylate | HCID 89498778 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [2-(2-Methoxyethyl)tricyclo[3.3.1.13,7]dec-2-yl]methanol | HCID 89498928 | — |
Reaction Steps
To a solution of EXAMPLE 56B (135 mg) in tetrahydrofuran (5 mL) was added dropwise lithium aluminum hydride (0.535 mL) at room temperature. The reaction mixture was stirred for 14 hours and sodium hydroxide (0.324 mL) was carefully added. The reaction mixture was stirred at room temperature for 60 minutes, filtered and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227963B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-5ca6dea5eb754d5d824d28de6bf5bfc3 |
| Source note | uspto-grants-2016_01 |