Methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylate → 1-Amino-2-chlorodibenzofuran-4-carboxylic acid

HRID 5887Notes

Reaction equation

HRID 5887 reaction equation
C([NH:4][C:5]1[C:13]2[CH:12]3[CH2:14][CH2:15][CH2:16][CH2:17][CH:11]3[O:10][C:9]=2[C:8]([C:18]([O:20]C)=[O:19])=[CH:7][C:6]=1[Cl:22])(=O)C.C(NC1C2C3CCCCC=3OC=2C(C(OC)=O)=CC=1Cl)(=O)C.C(NC1C2C3C=CC=CC=3OC=2C(C(OC)=O)=CC=1Cl)(=O)C>>[NH2:4][C:5]1[C:13]2[C:12]3[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=3[O:10][C:9]=2[C:8]([C:18]([OH:20])=[O:19])=[CH:7][C:6]=1[Cl:22]

Participants

4

Reactant 3

HCID 15136047Methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylateHCID 15136065Methyl 1-acetylamino-2-chloro-6,7,8,9-tetrahydrodibenzofuran-4-carboxylateHCID 15136066Methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate

Product 1

HCID 151360681-Amino-2-chlorodibenzofuran-4-carboxylic acid

Procedure

When the procedure of Example 15 is followed however methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylate is replaced by methyl 1-acetylamino-2-chloro-6,7,8,9-tetrahydrodibenzofuran-4-carboxylate or methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate then the captioned products are prepared.

Workup

  1. customthe captioned products are prepared

Sources & evidence

ORD record
ord-be42cc45ee0b43deb2da56f808879d43
Source dataset
uspto-grants-1993_09
Patent number
US05246942

Reaction notes

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