HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5-Dichloro-2-vinylbenzenamine → 4,5-Dichloro-2-ethylbenzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5-Dichloro-2-vinylbenzenamine | HCID 117607154 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4,5-Dichloro-2-ethylbenzenamine | HCID 21336848 | 80% |
Reaction Steps
A mixture of 4,5-dichloro-2-vinylbenzenamine (3.0 g, 15.95 mmol), Pd/C (3.3 g, 10%) in MeOH (20 mL) was stirred at room temperature under H2 (1 atm) atmosphere for 4 h. The mixture was filtered and the filtrate was concentrated in vacuo to afford the desired product (2.4 g, 80% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09227978B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-cc10df7abf0f42dcb0696e816e910d04 |
| Source note | uspto-grants-2016_01 |