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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 58911Generated: October 30, 2026

Trifluoroacetic acid → HCID 131737029, compound

https://huagongshe.com/reaction/58911

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant(S)-Benzyl 2-((tert-butoxycarbonyl)amino)-3-(pyridin-2-yl)propanoateHCID 15172404—
SolventDichloromethaneHCID 6344—
ProductHCID 131737029HCID 131737029—

Reaction Steps

To (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-(pyridin-2-yl)propanoate (0.558 g, 1.57 mmol) was added DCM (2 mL) followed by TFA (2 mL). The reaction mixture was allowed to stand for 1 h at which time it was concentrated to provide (S)-benzyl 2-amino-3-(pyridin-2-yl)propanoate TFA salt (quant. yield) as a yellow oil. MS (EI) for C17H16F3N2O3, found 257.2 [M-TFA]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434761B2
Source datasetuspto-grants-2016_09
ORD IDord-20a604e567934ad6b47155f6e2fe9c5b
Source noteuspto-grants-2016_09