HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 131737029, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (S)-Benzyl 2-((tert-butoxycarbonyl)amino)-3-(pyridin-2-yl)propanoate | HCID 15172404 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131737029 | HCID 131737029 | — |
Reaction Steps
To (S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-(pyridin-2-yl)propanoate (0.558 g, 1.57 mmol) was added DCM (2 mL) followed by TFA (2 mL). The reaction mixture was allowed to stand for 1 h at which time it was concentrated to provide (S)-benzyl 2-amino-3-(pyridin-2-yl)propanoate TFA salt (quant. yield) as a yellow oil. MS (EI) for C17H16F3N2O3, found 257.2 [M-TFA]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434761B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-20a604e567934ad6b47155f6e2fe9c5b |
| Source note | uspto-grants-2016_09 |