Cesium carbonate → 1319255-41-8

Participants

Reaction Steps

Cs2CO3 (651.6 mg, 2.0 mmol) and then FCH2Br (446.6 mg, 4.0 mmol) were added to a mixture of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (220 mg, 1.0 mmol)) in CH3CN (10 ml). After stirring at room temperature overnight, the mixture was filtered and concentrated. Purification by column chromatography afforded 2-(4-(fluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane: LCMS tR=1.39 Min (5 min run, UV254nm). Mass calculated for, M+ 252.1, observed LC/MS m/z 253.1 (M+H).

Provenance & Evidence