4-(4-{2-Hydroxymethyl-3-[6-(1-hydroxy-1-methyl-ethyl)-1-oxo-3,4-dihydro-1H-isoquinolin-2-yl]-phenyl}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide → 4-tert-Butyl-N-{3-[6-(3,6-dihydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-5-fluoro-2-methyl-phenyl}-benzamide

HRID 589514Notes

Reaction equation

CN(C)C(N1CC=C(C2NC3N=CN=C(C4C=C(F)C=C(N)C=4C)C=3C=2)CC1)=O.Cl[C:31]1[C:32]2[CH:39]=[C:38]([C:40]3[CH2:41][CH2:42][O:43][CH2:44][CH:45]=3)[NH:37][C:33]=2[N:34]=[CH:35][N:36]=1.CN(C)C(N1CC=C(C2NC3N=CN=C(C4C=CC=C(N5CCC6C(=CC=C(C(O)(C)C)C=6)C5=O)C=4CO)C=3C=2)CC1)=O.[C:89]([C:93]1[CH:118]=[CH:117][C:96]([C:97]([NH:99][C:100]2[CH:105]=[C:104]([F:106])[CH:103]=[C:102](B3OC(C)(C)C(C)(C)O3)[C:101]=2[CH3:116])=[O:98])=[CH:95][CH:94]=1)([CH3:92])([CH3:91])[CH3:90]>>[C:89]([C:93]1[CH:118]=[CH:117][C:96]([C:97]([NH:99][C:100]2[CH:105]=[C:104]([F:106])[CH:103]=[C:102]([C:31]3[C:32]4[CH:39]=[C:38]([C:40]5[CH2:41][CH2:42][O:43][CH2:44][CH:45]=5)[NH:37][C:33]=4[N:34]=[CH:35][N:36]=3)[C:101]=2[CH3:116])=[O:98])=[CH:95][CH:94]=1)([CH3:92])([CH3:90])[CH3:91]