HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butyl-N-{5-fluoro-3-[6-(4-hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide → 4-tert-Butyl-N-{3-[6 (4 hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butyl-N-{5-fluoro-3-[6-(4-hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide | HCID 71230891 | — |
| Reactant | 4-tert-Butyl-N-{2-methyl-3-[6-(4-oxo-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-phenyl}-benzamide | HCID 71231473 | — |
| Product | 4-tert-Butyl-N-{3-[6 (4 hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide | HCID 71230896 | — |
Reaction Steps
Example 66 was prepared analogue to Example 28 step 2 by replacing Intermediate 19 in with Intermediate 55.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233111B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-a5d4e241992444f98de87d53a542cfe8 |
| Source note | uspto-grants-2016_01 |