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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 589525Generated: October 30, 2026

4-tert-Butyl-N-{5-fluoro-3-[6-(4-hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide → 4-tert-Butyl-N-{3-[6 (4 hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamide

https://huagongshe.com/reaction/589525

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-Butyl-N-{5-fluoro-3-[6-(4-hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamideHCID 71230891—
Reactant4-tert-Butyl-N-{2-methyl-3-[6-(4-oxo-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-phenyl}-benzamideHCID 71231473—
Product4-tert-Butyl-N-{3-[6 (4 hydroxy-cyclohex-1-enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-phenyl}-benzamideHCID 71230896—

Reaction Steps

Example 66 was prepared analogue to Example 28 step 2 by replacing Intermediate 19 in with Intermediate 55.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233111B2
Source datasetuspto-grants-2016_01
ORD IDord-a5d4e241992444f98de87d53a542cfe8
Source noteuspto-grants-2016_01