2-Iodotoluene → HCID 11535877, compound

HRID 589530Notes

Reaction equation

I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH3:8].[CH2:9]([O:13][C:14](=[O:17])[CH:15]=[CH2:16])[CH2:10][CH2:11][CH3:12]>>[CH3:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1/[CH:16]=[CH:15]/[C:14]([O:13][CH2:9][CH2:10][CH2:11][CH3:12])=[O:17]

Participants

Reactant 2

HCID 51282-Iodotoluene

HCID 8846Butyl Acrylate

Product 1

HCID 11535877HCID 11535877, compound

Procedure

2-Iodotoluene (32 μL, 0.25 mmol) and n-butylacrylate (54 μL, 0.375 mmol) were coupled using the procedure described above to give 83% conversion to (E)-n-butyl 3-(2-methylphenyl)acrylate by GC analysis.

Sources & evidence

ORD record: ord-099e562977fa496284c4305049d35f55
Source dataset: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09233366B2

Reaction notes

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