Water → HCID 178524755, compound

HRID 589547Notes

Reaction equation

HRID 589547 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]([OH:10])=[O:9].[OH2:11]>>[OH:11][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[C:8]([OH:10])=[O:9]

Participants

3

Reactant 2

HCID 962WaterHCID 8182294-Chloronicotinic acid

Product 1

HCID 178524755HCID 178524755, compoundYield 80%

Procedure

Compound 3 is heated in water (see ROSS, J. Chem. Soc. (C), p. 1816-1821, 1966) to obtain 4-hydroxypyridine-3-carboxylic acid 5 as a colorless solid (>80%).

Sources & evidence

ORD record
ord-7db93ab561ed407f8f3e67002bb3cd7e
Source dataset
uspto-grants-2016_01
Patent number
US09233931B2

Reaction notes

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