5-(1,3-Oxazol-5-Yl)-2-Thiophenesulfonyl Chloride → HCID 178527495, compound

HRID 589681Notes

Reaction equation

HRID 589681 reaction equation
[O:1]1[C:5]([C:6]2[S:10][C:9]([S:11](Cl)(=[O:13])=[O:12])=[CH:8][CH:7]=2)=[CH:4][N:3]=[CH:2]1.[NH2:15][C:16]1[CH:17]=[C:18]([C:22]2[NH:26][N:25]=[N:24][N:23]=2)[CH:19]=[CH:20][CH:21]=1>>[O:1]1[C:5]([C:6]2[S:10][C:9]([S:11]([NH:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([C:22]4[NH:26][N:25]=[N:24][N:23]=4)[CH:17]=3)(=[O:13])=[O:12])=[CH:8][CH:7]=2)=[CH:4][N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 27764115-(1,3-Oxazol-5-Yl)-2-Thiophenesulfonyl ChlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527495HCID 178527495, compoundYield 52%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, starting with 5-(1,3-oxazol-5-yl)thiophene-2-sulfonyl chloride (13.7 mg, 0.055 mmol) and 5-(3-amino-phenyl)tetrazole (8 mg, 0.05 mmol) yielding 9.7 mg (52%) of the title compound. MS (ESI+) calcd for C14H10N6O3S2 374.02558, found 374.02547.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-8866328eee594f13ad19b1fc1ae66249
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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