3-(4-methoxyphenyl)benzenesulfonyl Chloride → HCID 178488590, compound

HRID 589688Notes

Reaction equation

HRID 589688 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[C:11]([S:15](Cl)(=[O:17])=[O:16])[CH:12]=[CH:13][CH:14]=2)=[CH:5][CH:4]=1.[NH2:19][C:20]1[CH:21]=[C:22]([C:26]2[NH:30][N:29]=[N:28][N:27]=2)[CH:23]=[CH:24][CH:25]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15]([NH:19][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]4[NH:30][N:29]=[N:28][N:27]=4)[CH:21]=3)(=[O:17])=[O:16])[CH:10]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 49887373-(4-methoxyphenyl)benzenesulfonyl ChlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178488590HCID 178488590, compoundYield 60%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, starting from [3-(4-methoxyphenyl)phenyl]sulfonyl chloride (16 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8 mg, 0.05 mmol) giving 12 mg (60%) of the title compound. MS (ESI+) calcd for C20H17N5O3S 407.10521, found 407.10532.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-fd5a27487f514d8391143619491a97cd
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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