2-Naphthalenesulfonyl chloride → HCID 178527476, compound

HRID 589689Notes

Reaction equation

HRID 589689 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11](Cl)(=[O:13])=[O:12].[NH2:15][C:16]1[CH:17]=[C:18]([C:22]2[NH:26][N:25]=[N:24][N:23]=2)[CH:19]=[CH:20][CH:21]=1>>[NH:26]1[C:22]([C:18]2[CH:17]=[C:16]([NH:15][S:11]([C:2]3[CH:3]=[CH:4][C:5]4[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=4)[CH:1]=3)(=[O:13])=[O:12])[CH:21]=[CH:20][CH:19]=2)=[N:23][N:24]=[N:25]1

Participants

3

Reactant 2

HCID 71252-Naphthalenesulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527476HCID 178527476, compoundYield 57%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, starting from 2-naphthalenesulfonyl chloride (13 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8 mg, 0.05 mmol) giving 10 mg (57%) of the title compound. MS (ESI+) calcd for C17H13N5O2S 351.078995, found 351.080505

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-5ff3eb64206248f9ad03bd521a683c1e
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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