(1,1'-Biphenyl)-4-sulphonyl chloride → HCID 178527480, compound

HRID 589700Notes

Reaction equation

HRID 589700 reaction equation
[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[NH:17]1[C:21]([C:22]2[CH:23]=[C:24]([NH2:28])[CH:25]=[CH:26][CH:27]=2)=[N:20][N:19]=[N:18]1>>[NH:20]1[C:21]([C:22]2[CH:23]=[C:24]([NH:28][S:7]([C:4]3[CH:5]=[CH:6][C:1]([C:11]4[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=4)=[CH:2][CH:3]=3)(=[O:9])=[O:8])[CH:25]=[CH:26][CH:27]=2)=[N:17][N:18]=[N:19]1

Participants

3

Reactant 2

HCID 74192(1,1'-Biphenyl)-4-sulphonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178527480HCID 178527480, compoundYield 60%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, starting from biphenyl-4-sulfonyl chloride (14 mg, 0.055 mmol) and [3-(1H-tetrazol-5-yl)phenyl]amine (8 mg, 0.05 mmol) giving 11 mg (60%) of the title product. MS (ESI+) calcd for C19H15N5O2S 377.094645, found 377.094375.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-964a73ccf9894b7382df140f80992d6d
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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