Lithium Hexamethyldisilazide → HCID 178432002, compound

Participants

Reaction Steps

The product was prepared from 5-bromo-3-methyl-N-[3-(1H-tetrazol-5-yl)phenyl]-1-benzothiophene-2-sulfonamide (Example 34) (45 mg, 0.1 mmol) and LiHMDS (1M in THF, 120 μL, 0.12 mmol) according to the General Procedure 4, described in Example 45, using a modified reaction time (130° C., 300 s, microwave reactor). The title compound was obtained in 2% yield (0.6 mg). MS (ESI+) calcd for C16H14N6O2S2 386.061965, found 386.061875.

Provenance & Evidence