2,4-Dichloro-6-methylbenzenesulfonyl chloride → HCID 178426115, compound

HRID 589723Notes

Reaction equation

HRID 589723 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([CH3:9])[C:3]=1[S:10](Cl)(=[O:12])=[O:11].[NH2:14][C:15]1[CH:16]=[C:17]([C:21]2[NH:25][N:24]=[N:23][N:22]=2)[CH:18]=[CH:19][CH:20]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([CH3:9])[C:3]=1[S:10]([NH:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([C:21]2[NH:25][N:24]=[N:23][N:22]=2)[CH:16]=1)(=[O:12])=[O:11]

Participants

3

Reactant 2

HCID 28013872,4-Dichloro-6-methylbenzenesulfonyl chlorideHCID 178507542HCID 178507542, compound

Product 1

HCID 178426115HCID 178426115, compoundYield 80%

Procedure

The product was prepared according to General Procedure 1, described in Example 1, starting with 2,4-dichloro-6-methylbenzene sulfonyl chloride (14.3 mg, 0.055 mmol) and 5-(3-aminophenyl)tetrazole (8 mg, 0.05 mmol) yielding 15.3 mg (80%) of the title compound. MS (ESI+) calcd for C14H11Cl2N5O2S 383.001051, found 383.001071.

Workup

  1. customThe product was prepared

Sources & evidence

ORD record
ord-4877506f8d694e7d80d1e722e55941e4
Source dataset
uspto-grants-2016_01
Patent number
US09233946B2

Reaction notes

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