HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminobenzoic Acid → 3-{[(5-Isoxazol-3-yl-2-thienyl)sulfonyl]amino}benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminobenzoic Acid | HCID 7419 | — |
| Reactant | 5-(Isoxazol-3-yl)thiophene-2-sulfonyl chloride | HCID 2797180 | — |
| Product | 3-{[(5-Isoxazol-3-yl-2-thienyl)sulfonyl]amino}benzoic acid | HCID 56942026 | 55% |
Reaction Steps
The product was prepared according to General Procedure 6, described in Example 65, with 5-isoxazol-3-ylthiophene-2-sulfonyl chloride (13.7 mg, 0.055 mmol) and 3-aminobenzoic acid (6.9 mg, 0.050 mmol). The title compound was obtained in 55% yield (9.6 mg). MS (ESI+) calcd mass for C14H10N2O5S2 350.003113, found 350.002783.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233946B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-4f9e7817196546e5b8dd247635aa6c05 |
| Source note | uspto-grants-2016_01 |