Methyl 2-aminothiazole-5-carboxylate → HCID 86689198, compound

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Reaction Steps

The product was prepared from methyl 2-amino-1,3-thiazole-5-carboxylate (7.9 mg, 0.050 mmol) and 5-chloro-3-methyl-benzothiophene-2-sulfonyl chloride (14 mg, 0.050 mmol) according to the General Procedure 10, described in Example 128. The title compound was obtained in 35% yield (6.8 mg). 1H NMR (500 MHz, MeOH-d4) δ ppm 2.65 (s, 3 H) 7.47 (dd, J=8.67, 2.08 Hz, 1 H) 7.80 (s, 1 H) 7.88 (dd, J=8.67, 0.57 Hz, 1 H) 7.90 (dd, J=2.08, 0.57 Hz, 1 H). MS (ESI+) m/z 389 [M+H]+.

Provenance & Evidence