HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86706432, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68296099 | HCID 68296099 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86706432 | HCID 86706432 | — |
Reaction Steps
4-[4-(3-Cyano-propylsulfamoyl)-4,7-diaza-spiro[2.5]oct-7-yl]-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester (intermediate 18) was dissolved in THF (1 mL), added TFA (0.5 mL) and then stirred at rt for 2 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233964B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-14dcda14303441269c6b29eca09ad439 |
| Source note | uspto-grants-2016_01 |