HRID589984

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

$结构：COc1ccc(/C=N\S(=O)(=O)N2CCN(c3ncnc4[nH]ccc34)CC23CC3)cc1$

HCID118649767

未命名化合物

2 次

PRODUCTS

生成物

结构：COc1ccc(CNS(=O)(=O)N2CCN(c3ncnc4[nH]ccc34)CC23CC3)cc1

HCID57410101

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

(NZ)—N-[(4-methoxyphenyl)methylene]-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5,8-diazaspiro[2.5]octane-8-sulfonamide (intermediate 49) was dissolved in MeOH, added NaBH4 (1 eq) and stirred at rt for 2 h. The pure compound was obtained by standard preparative HPLC purification of the reaction mixture.

WORKUP

后处理

customThe pure compound was obtained by standard preparative HPLC purification of the reaction mixture