反应详情

The reaction was conducted for 15 minutes in the same experimental procedures as in Example 16 except for using 4,4′-dibromobiphenyl (9.8 g, 31.6 mol, 1.0 equivalent) as an aryl halide. To the reaction mixture was added an aqueous solution of ammonium chloride, and the mixture was poured into chloroform (500 mL). The aqueous layer was separated off, and the organic layer was passed through a silica gel pad and concentrated to remove the excess chloroform under reduced pressure. To the thus-obtained suspension was added methanol (150 mL), and the crystal was collected from the suspension by suction filtration, washed with methanol and dried under reduced pressure to afford 14.9 g of CBP as a pale yellow powder.

1. customThe aqueous layer was separated off
2. concentrationconcentrated
3. customto remove the excess chloroform under reduced pressure
4. additionTo the thus-obtained suspension was added methanol (150 mL)
5. filtrationthe crystal was collected from the suspension by suction filtration
6. washwashed with methanol
7. customdried under reduced pressure
8. customto afford 14.9 g of CBP as a pale yellow powder