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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590296Generated: October 30, 2026

Ammonium Hydroxide → HCID 57989907, compound

https://huagongshe.com/reaction/590296

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantHCID 86636596HCID 86636596—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 57989907HCID 57989907—

Reaction Steps

Following a procedure analogous to the procedure described in Example 52, Step B using N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-3-furansulfonamide (100 mg, 0.192 mmol) and ammonium hydroxide (4 mL) and 1,4-Dioxane (1 mL), the title compound was obtained as an off-white solid (65 mg, 64% yield). MS (ESI): 503 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233956B2
Source datasetuspto-grants-2016_01
ORD IDord-4b73392ffb6c4d3898c65357a0aa65a1
Source noteuspto-grants-2016_01