HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 57989907, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 86636596 | HCID 86636596 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 57989907 | HCID 57989907 | — |
Reaction Steps
Following a procedure analogous to the procedure described in Example 52, Step B using N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-3-furansulfonamide (100 mg, 0.192 mmol) and ammonium hydroxide (4 mL) and 1,4-Dioxane (1 mL), the title compound was obtained as an off-white solid (65 mg, 64% yield). MS (ESI): 503 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233956B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-4b73392ffb6c4d3898c65357a0aa65a1 |
| Source note | uspto-grants-2016_01 |