HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dibromobutane → 2-(Butyloxy)-8-(methyloxy)-9-[4-(1-piperidinyl)butyl]-9H-purin-6-amine formic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 9-[3-(1-Azetidinyl)propyl]-2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine | HCID 59252600 | — |
| Reactant | HCID 178450357 | HCID 178450357 | — |
| Product | 2-(Butyloxy)-8-(methyloxy)-9-[4-(1-piperidinyl)butyl]-9H-purin-6-amine formic acid salt | HCID 66727006 | — |
Reaction Steps
Prepared similarly to Intermediate 20 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate, 1,4-dibromobutane and piperidine but with sequential mass directed autopreparations using Method A followed by Method D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233962B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-cb6cbd25cc7149b28ef1d58ff26a502e |
| Source note | uspto-grants-2016_01 |