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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590465Generated: October 30, 2026

1-Bromo-5-chloropentane → 9-(5-Chloropentyl)-2-[(1-methylethyl)oxy]-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/590465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-5-chloropentaneHCID 96070—
Reactant9-(4-Chlorobutyl)-8-(methyloxy)-2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amineHCID 59252648—
ReactantHCID 178494011HCID 178494011—
Product9-(5-Chloropentyl)-2-[(1-methylethyl)oxy]-8-(methyloxy)-9H-purin-6-amineHCID 59252633—

Reaction Steps

Prepared similarly to Intermediate 44 from 2-[(1-methylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 1-bromo-5-chloropentane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233962B2
Source datasetuspto-grants-2016_01
ORD IDord-91138da240d544279920d650103022b3
Source noteuspto-grants-2016_01