反应详情

A mixture of 1-(3-nitrophenyl)-1,4-dihydro-5H-tetrazol-5-one (130 mg, 0.63 mmol) and palladium on charcoal (Aldrich Cat. No. 330108; 13 mg) in MeOH (10 mL) was hydrogenated at 20 psi for 3 hr. The mixture was then filtered through celite and the filter cake washed with MeOH (×3). The filtrate was concentrated under vacuum to leave the product, which was used directly in the next step (yield assumed quantitative=111 mg).

1. filtrationThe mixture was then filtered through celite
2. washthe filter cake washed with MeOH (×3)
3. concentrationThe filtrate was concentrated under vacuum
4. customto leave the product, which
5. customwas used directly in the next step (yield assumed quantitative=111 mg)