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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590472Generated: October 26, 2026

2-(Cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → 8-Bromo-2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

https://huagongshe.com/reaction/590472

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252629—
Reactant8-Bromo-2-(cyclobutyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252642—
Product8-Bromo-2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252655—

Reaction Steps

Prepared similarly to Intermediate 56 from 2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233962B2
Source datasetuspto-grants-2016_01
ORD IDord-5631f1c5692c4e43af6172fdff485a73
Source noteuspto-grants-2016_01