HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-nitro-6,7-dihydrobenzo[b]thiophen-4(5H)-one → 2-amino-6,7-dihydrobenzo[b]thiophen-4(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-nitro-6,7-dihydrobenzo[b]thiophen-4(5H)-one | HCID 762878 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-amino-6,7-dihydrobenzo[b]thiophen-4(5H)-one | HCID 90070480 | — |
Reaction Steps
2-Nitro-6,7-dihydrobenzo[b]thiophen-4(5H)-one (3.6 g, 18.2 mmol) was dissolved in DMF (50 mL) and stirred under an atmosphere of hydrogen (300 psi) for 18 hr with 10% palladium on carbon. The mixture was filtered through celite and used directly in the next step as a solution in DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233982B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-90e65dbcae674d169afaea76ac05320c |
| Source note | uspto-grants-2016_01 |