Water → HCID 71548967, compound

Participants

Reaction Steps

A solution of azide 19 (0.60 mmol) and bicyclodiene 20 (0.31 mL, 3.03 mmol) in dioxane (4.0 mL) is refluxed for 5 h. Water (5 mL) is added and extracted with DCM (2×5 mL), dried and concentrated. The product is further purified by column chromatography on silica using hexane-EtOAc mixtures to obtain the product as a brown solid (60 mg) in 26% over 3 steps.

Provenance & Evidence