HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-amino-3-methylbutanoate hydrochloride → 3-[(8aS)-3-oxo-1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazin-2-yl]-3-methyl-butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-amino-3-methylbutanoate hydrochloride | HCID 19371621 | — |
| Reactant | (S)-2,2-Dimethyl-3-(3-oxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl)propanoic acid | HCID 118354187 | — |
| Product | 3-[(8aS)-3-oxo-1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyrazin-2-yl]-3-methyl-butanoic acid | HCID 118354422 | — |
Reaction Steps
The title compound was prepared in analogy to Compound Q in Example 19 by using methyl 3-amino-3-methyl-butanoate hydrochloride salt (Compound AP-1) instead of ethyl 3-amino-2,2-dimethyl-propanoate hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233978B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-8de739ba31044e43a886f5635f1ca596 |
| Source note | uspto-grants-2016_01 |