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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590579Generated: October 25, 2026

Methyl 3-amino-2-methylpropanoate hydrochloride → Methyl 3-(aminomethyl)cyclobutanecarboxylate hydrochloride

https://huagongshe.com/reaction/590579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-amino-2-methylpropanoate hydrochlorideHCID 13063725—
Reactant3-(Aminomethyl)cyclobutanecarboxylic acidHCID 58557901—
ProductMethyl 3-(aminomethyl)cyclobutanecarboxylate hydrochlorideHCID 86222900—

Reaction Steps

Compound 81-B was prepared in analogy to compound W in Example 20 by using 3-(aminomethyl)cyclobutanecarboxylic acid (PharmaBlock (Nanjing) R&D Co. Ltd, CAS: 1310729-95-3) instead of DL-3-aminoisobutyric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233978B2
Source datasetuspto-grants-2016_01
ORD IDord-507c8b89e31741bbb337bddb82b33a5c
Source noteuspto-grants-2016_01