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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590583Generated: October 31, 2026

Methyl acetoacetate → HCID 118358808, compound

https://huagongshe.com/reaction/590583

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl acetoacetateHCID 7757—
ReactantEthyl AcetoacetateHCID 8868—
Reactant3,4-Difluoro-2-methylbenzaldehydeHCID 12137681—
ReactantMethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylateHCID 89995948—
ProductHCID 118358808HCID 118358808—

Reaction Steps

Compound C-7 was prepared in analogy to compound C by using 3,4-difluoro-2-methylbenzaldehyde and ethyl acetoacetate instead of 2-chloro-4-fluorobenzaldehyde and methyl acetoacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233978B2
Source datasetuspto-grants-2016_01
ORD IDord-e954e5cdb7834e349f6776186cb5f6c9
Source noteuspto-grants-2016_01