Isobutylamine → HCID 131734491, compound
Reaction equation
[CH:1]1([N:4]2[CH2:16][C@@H:7]3[C@H:8]([C:12]([O:14][CH3:15])=[O:13])[NH:9][CH2:10][CH2:11][N:6]3[C:5]2=[O:17])[CH2:3][CH2:2]1.[CH3:18]C(C)CN>>[CH2:1]([N:4]1[CH2:16][C@@H:7]2[C@H:8]([C:12]([O:14][CH3:15])=[O:13])[NH:9][CH2:10][CH2:11][N:6]2[C:5]1=[O:17])[CH:3]([CH3:2])[CH3:18]Participants
3
Procedure
Compound 101-C was prepared in analogy to compound 82-C by using 2-methylpropan-1-amine instead of cyclopropylamine.
Sources & evidence
- ORD record
- ord-5083cf9457d84c24988bb02c0e03a471
- Source dataset
- uspto-grants-2016_01
- Patent number
- US09233978B2
Reaction notes
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