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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590586Generated: October 30, 2026

Trifluoroacetic acid → HCID 84110985, compound

https://huagongshe.com/reaction/590586

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 118358833HCID 118358833—
SolventDichloromethaneHCID 6344—
ProductHCID 84110985HCID 84110985—

Reaction Steps

tert-Butyl 2-isopropyl-3-oxo-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazine-7-carboxylate (compound 104-C-1) (1 mmol) was dissolved in CH2Cl2 (3 mL) followed by the slow addition of TFA (1 mL) at 0° C. After the reaction mixture was stirred at rt for 1 hour, the solvent was removed in vacuum to give the crude product 104-C, which was used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09233978B2
Source datasetuspto-grants-2016_01
ORD IDord-42bfef8a5c454bfbb84e4983b9849055
Source noteuspto-grants-2016_01