HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 84110985, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 118358833 | HCID 118358833 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 84110985 | HCID 84110985 | — |
Reaction Steps
tert-Butyl 2-isopropyl-3-oxo-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazine-7-carboxylate (compound 104-C-1) (1 mmol) was dissolved in CH2Cl2 (3 mL) followed by the slow addition of TFA (1 mL) at 0° C. After the reaction mixture was stirred at rt for 1 hour, the solvent was removed in vacuum to give the crude product 104-C, which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233978B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-42bfef8a5c454bfbb84e4983b9849055 |
| Source note | uspto-grants-2016_01 |