HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67386995, compound → HCID 15719911, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67386995 | HCID 67386995 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15719911 | HCID 15719911 | 97% |
Reaction Steps
A mixture of (S)-1-tert-butyl 2-methyl 4-ethylidenepyrrolidine-1,2-dicarboxylate (50 g, 196 mmol), Pd/C (5 g) in EtOH (500 mL) was hydrogenated at room temperature overnight. The mixture was filtered and concentrated to afford (2S)-1-tert-butyl 2-methyl 4-ethylpyrrolidine-1,2-dicarboxylate (9.8 g, 97%) as colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09233974B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-20f9db38991b45abb873eb68c9d892ff |
| Source note | uspto-grants-2016_01 |