1-Tetradecanol → Myristyl myristate

HRID 590681Notes

Reaction equation

HRID 590681 reaction equation
[CH2:1]([OH:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[C:16](O)(=[O:30])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]>>[C:1]([O:30][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])(=[O:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 82091-TetradecanolHCID 11005Myristic Acid

Product 1

HCID 18605Myristyl myristate

Conditions

Temperature
60 °C

Procedure

329 g of myristyl alcohol and 351 g of myristic acid were heated to 60° C. in a 1 l reservoir vessel and mixed by means of a magnetic stirrer (viscosity of the mixture at 60° C. approx. 6 mPas). The lower region of the reaction vessel was initially charged with 2.7 g of NOVOZYM 435 and the entire reaction vessel was heated to 60° C. The compressed air introduction was regulated to 0.4 l/min and then the peristaltic pump was set to ˜20 ml/min and switched on. The reflux was heated to 60° C. The course of the reaction was monitored for ˜25 h, and a conversion of 99.3% based on the fatty acid was achieved.

Workup

  1. additionmixed by means of a magnetic stirrer (viscosity of the mixture at 60° C. approx
  2. additionThe lower region of the reaction vessel was initially charged with 2.7 g of NOVOZYM 435
  3. temperatureThe reflux was heated to 60° C

Sources & evidence

ORD record
ord-af4dc88f07f941cca3e8818e15557d79
Source dataset
uspto-grants-2016_01
Patent number
US09234220B2

Reaction notes

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