Azobisisobutyronitrile → HCID 118272051, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 4,6-dichloro-2-methylnicotinonitrile (2.15 g, 11.50 mmol) in CCl4 (45 ml) was charged with AIBN (1.93 g, 11.75 mmol) and NBS (4.37 g, 24.55 mmol), sealed and heated to 75° C. for 16 hr. The mixture was poured directly onto SiO2 and purified via flash chromatography (5-15% Et2O/hexane) to provide 2-(bromomethyl)-4,6-dichloronicotinonitrile. MS ESI calc'd. for C7H4BrC12N2 [M+H]+ 265. found 265.

Provenance & Evidence