HCID 118390791, compound → HCID 118390790, compound

Participants

Reaction Steps

To a solution of tert-butyl(6-(((benzyloxy)carbonyl)amino)-1-trityl-1H-pyrazolo[4,3-c]pyridin-3-yl)(ethyl)carbamate (0.2 g, 0.31 mmol) in MeOH (50 mL) was added Pd on carbon (10%, 0.2 g) and the contents were stirred under an atmosphere of H2 (3.0 Kg/cm2). After 5 h, the suspension was filtered through a pad of celite, and the solvent was evaporated under reduced pressure to afford the title compound (0.12 g, 75% yield) and was taken directly for the next step. MS ESI calc'd. for C32H33N5O2 [M+H]+ 520. Found 520.

Provenance & Evidence