2-Chloronicotinoyl chloride → HCID 86656686, compound

HRID 590910Notes

Reaction equation

HRID 590910 reaction equation
[NH2:1][C:2]1[C:3]([F:29])=[C:4]([CH:26]=[CH:27][CH:28]=1)[C:5]([NH:7][C:8]1[C:13]([Br:14])=[CH:12][C:11]([C:15]([F:24])([C:20]([F:23])([F:22])[F:21])[C:16]([F:19])([F:18])[F:17])=[CH:10][C:9]=1[Br:25])=[O:6].[Cl:30][C:31]1[N:39]=[CH:38][CH:37]=[CH:36][C:32]=1[C:33](Cl)=[O:34]>>[Cl:30][C:31]1[N:39]=[CH:38][CH:37]=[CH:36][C:32]=1[C:33]([NH:1][C:2]1[CH:28]=[CH:27][CH:26]=[C:4]([C:5](=[O:6])[NH:7][C:8]2[C:9]([Br:25])=[CH:10][C:11]([C:15]([F:24])([C:16]([F:17])([F:18])[F:19])[C:20]([F:21])([F:22])[F:23])=[CH:12][C:13]=2[Br:14])[C:3]=1[F:29])=[O:34]

Participants

3

Reactant 2

HCID 27745412-Chloronicotinoyl chlorideHCID 86654231HCID 86654231, compound

Product 1

HCID 86656686HCID 86656686, compound

Procedure

According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide and 2-chloronicotinic acid chloride.

Sources & evidence

ORD record
ord-f342954ad55c4a109f699a791f9e9a5f
Source dataset
uspto-grants-2016_01
Patent number
US09237745B2

Reaction notes

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