HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chlorothiazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Chloro-1,3-thiazole-4-carboxylic acid | HCID 21803026 | — |
| Reactant | 2-Chloro-1,3-thiazole-4-carbonyl chloride | HCID 45081536 | — |
| Reactant | 2-Bromo-4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-6-(trifluoromethyl)benzenamine | HCID 58297558 | — |
| Product | N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chlorothiazole-4-carboxamide | HCID 86654249 | — |
Reaction Steps
According to the method of 4-3 of Example 4, a target compound was prepared from 2-chlorothiazole-4-carbonylchloride prepared from 2-chlorothiazole-4-carboxylic acid and thionyl chloride, and 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09237745B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-a1ba2c172d1c429d8b0221c1e3b9a963 |
| Source note | uspto-grants-2016_01 |