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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 590924Generated: October 25, 2026

Thionyl Chloride → N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-nitrobenzamide

https://huagongshe.com/reaction/590924

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant4-Iodo-3-nitrobenzoic acidHCID 11208598—
Reactant2-Chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)anilineHCID 58297418—
Reactant4-Iodo-3-nitrobenzoyl chlorideHCID 58932935—
ProductN-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-nitrobenzamideHCID 86654250—

Reaction Steps

According to the method of 1-3 of Example 1, a target compound was prepared from 4-iodo-3-nitrobenzoyl chloride prepared from 4-iodo-3-nitrobenzoic acid and thionyl chloride, and 2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09237745B2
Source datasetuspto-grants-2016_01
ORD IDord-f95d50db96684ba6b950c4d83e7ced37
Source noteuspto-grants-2016_01