HCID 86717831, compound → HCID 86717833, compound

Participants

Reaction Steps

Under nitrogen atmosphere, manganese dioxide (318 mg, 3.65 mmol) was added to a solution of {1-bromothieno[3,2-f]quinolin-2-yl}methanol (16e) (215 mg, 0.731 mmol) in dichloromethane (31 mL) at room temperature. The mixture was vigorously stirred for 7 hours, then it was filtered and concentrated to give the desired aldehyde (16f) as a yellow solid (170 mg, 0.58 mmol, 58%)

Provenance & Evidence